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Virusne infekcije

Askaa J, Bloch B, Bertelsen G, Rasmussen KO. Nord Vet Med. 1983 Dec;35(12):441-7. Related Articles, Links, Rotavirus associated diarrhoea in nursing piglets and detection of antibody against rotavirus in colostrum, milk and serum.

Brussow, H, Hilpert, H, Walther, I, Sidoti, J, Mietens, C, Bachmann, P. Bovine milk immunoglobulins for passive immunity to infantile rotavirus gastroenteritis. Journal of Clinical Microbiology 25(6):982-986 (1987).

Boesman-Finkelstein M, Finkelstein RA. Lancet. 1989 Dec 2;2(8675):1336. Related Articles, Links, Comment on: Lancet. 1989 Sep 23;2(8665):709-12. Passive oral immunisation of children.

Chan, MC, Cheung, CY, Chui, WH, Tsao, SW, Nicholls, JM, Chan, YO, Chan, RW, Long, HT, Poon, LL, Guan, Y, Peiris, JS. Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells. Respiratory Research 6:135 (2005).

Davidson, G.P.; E.; Nunan, H.; Moore, A..G.; Whyte, P.B.D.; Franklin, K.; McCloud, P.L.; Moore, D.J. Passive Immunization of children with bovine colostrum containing antibodies to human rotavirus. Lancet. 2:709-712, 1989.

Ebina, T, Sato, A, Umezu, K, Ishida, N, Ohyama, S, Ohizumi, A, Aikawa, K, Katagiri, S, Katsushima, N, Imai, A. Prevention of rotavirus infection by cow colostrum antibody against human rotaviruses. Lancet 2(8357):1029-1030 (1983).

Ebina, T, Ohta, M, Kanamaru, Y, Yamamoto-Osumi, Y, Baba, K. Passive immunizations of suckling mice and infants with bovine colostrum containing antibodies to human rotavirus. Journal of Medical Virology 38(2):117-123 (1992).

Ebina, T. Prophylaxis of rotavirus gastroenteritis using immunoglobulin. Archives of Virology Supplement 12:217-223 (1996).

Ferrer-Argote, VE, Romero-Cabello, R, Hernandez-Mendoza, L, Arista-Viveros, A, Rojo-Medina, J, Balseca-Olivera, F, Fierro, M, Gonzalez-Constandse, R. Successful treatment of severe complicated measles with non-specific transfer factor. In Vivo 8(4):555-557 (1994).

Farthing MJ., Treatment of gastrointestinal viruses., Novartis Found Symp. 2001;238:289-300; discussion 300-5. Related Articles, Links, Digestive Diseases Research Centre, St Bartholomew's & Royal London School of Medicine & Dentistry, Turner Street, London E1 2AD, UK.

Hasegawa, K., et, al. Inhibition with lactoferrin of in vitro infection with human herpes virus. Japanese Journal of Medical Science and Biology. 47(2):73-85, Apr 1994.

Hilpert, H, Brussow, H, Mietens, C, Sidoti, J, Lerner, L, Werchau, H. Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants. Journal of Infectious Disease 156(1):58-166 (1987).

Hoffman M. (1992) Transferred immune cells may help fight viral infection. Immunology. 257(5067):166.

Immunoglobulin components and anti-viral activities in bovine colostrum. Kansenshogaku Zasshi. 1990 Mar;64(3):274-9.

Khan, A. Transfer factor in viral diseases. The Lancet 1(8059):328-329 (1978).

Kohl, S. et al., Human colostral cytotoxicity: antibody-dependent cellular cytotoxicity against herpes simplex infected cells mediated by colostral cells. Journal of Clinical Laboratory Immunology, 1, pp. 221-224.

Meduri, R, Campos, E, Scorolli, L, De Vinci, C, Pizza, G, Viza, D. Efficacy of transfer factor in treating patients with recurrent ocular herpes infections. Biotherapy 9(1-3):61-66 (1996).

Mitra AK, Mahalanabis D, Ashraf H, Unicomb L, Eeckels R, Tzipori S. Acta Paediatr. 1995 Sep;84(9):996-1001. Related Articles, Links, Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double-blind, controlled clinical trial. International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka Bangladesh.

Mitra AK, Mahalanabis D, Ashraf H, Unicomb L, Eeckels R, Tzipori S. Acta Paediatr. 1995 Sep;84(9):996-1001. Related Articles, Links, Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double-blind, controlled clinical trial. International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka Bangladesh.

Orzechowska, B., et al. “Antiviral effect of proline-rich polypeptide in murine resident peritoneal cells.” Acta Virol; 1998;42(2):75-78.

Orzechowska, B, Blach-Olszewska, Z. Acquisition of susceptibility to vesicular stomatitis virus infection by murine resident peritoneal cells during culturing in vitro. Archivum immunologiae et therapiae experimentalis (Warszava) 44(5-6):325-328 (1996).

Orzechowska, B, Janusz, M, Domaraczenko, B, Blach-Olszewska, Z. Antiviral effect of proline-rich polypeptide in murine resident peritoneal cells. Acta Virologica 42(2):75-78 (1998).

Palmer,E.L. et al. Antiviral Activity of Colostrum and Serum Immunoglobulins A and G. J. Med. Virol. 5:123-129. 1980.

Petschow, BW, Talbott, RD. Reduction in virus-neutralizing activity of a bovine colostrum immunoglobulin concentrate by gastric acid and digestive enzymes. Journal of Pediatric Gastroenterology and Nutrition 19(2):228-235 (1994).

Pizza, G, Meduri, R, De Vinci, C, Scorolli, L, Viza, D. Transfer factor prevents relapses in herpes keratitis patients: a pilot study. Biotherapy 8(1):63-68 (1994).

Pizza, G, Viza, D, De Vinci, C, Palareti, A, Cuzzocrea, D, Fornarola, V, Baricordi, R. Orally administered HSV-specific transfer factor (TF) prevents genital or labial herpes relapses. Biotherapy 9(1-3):67-72 (1996).

Pizza, G, Amadori, M, Ablashi, D, De Vinci, C, Viza, D. (2006). Cell mediated immunity to meet the avian influenza A (H5N1) challenge. Medical Hypoteses 67(3):601-8. As no vaccine can be made ahead of time for a possible bird flu pandemic, cell mediated immunity via specific transfer factor (PRP) may be useful for both the prevention and treatment of infection.

Prasad, U, bin Jalaludin, MA, Rajadurai, P, Pizza, G, De Vinci, C, Viza, D, Levine, PH. Transfer factor with anti-EBV activity as an adjuvant therapy for nasopharyngeal carcinoma: a pilot study. Biotherapy 9(1-3):109-115 (1996).

"Reducing viral levels in the body and stimulating natural immune capabilities holds the most promise in helping our immune systems contain the HIV virus," according to Dr. Nowa and Dr. McMichael in Scientific American.

Rump JA, Arndt R, Arnold A, Bendick C, Dichtelmuller H, Franke M, Helm EB, Jager H, Kampmann B, Kolb P, et al. Treatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrum. Clin Investig. 1992 Jul;70(7):588-94.

Qiu, J, Hendrixson, DR, Baker, EN, Murphy,TF, St. Geme, JW, III, Plaut, AG. Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae. Proceedings of the National Academy of Science (USA) 95(21):12641-12646 (1998).

Shortridge, KF, Lawton, JW, Choi, EK. Protective potential of colostrum and early milk against prospective influenza viruses. Journal of Tropical Pediatrics 36(2):94-95 (1990).

Sarker, SA, Casswall, TH, Mahalanabis, D, Alam, NH, Albert, MJ, Brussow, H, Fuchs, GJ, Hammerstrom, L. Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum. Pediatric Infectious Disease Journal 17(12):1149-1152 (1998).

Saif LJ, Smith KL.Enteric viral infections of calves and passive immunity. J Dairy Sci. 1985 Jan;68(1):206-28.

Sarker SA, Casswall TH, Mahalanabis D, Alam NH, Albert MJ, Brussow H, Fuchs GJ, Hammerstrom L.Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum. Pediatr Infect Dis J.1998 Dec;17(12):1149-54.

Sabin, A and Fieldsteel, A.H. Antipoliomyelitic activity of human and bovine colostrum and milk. Pediatrics, Jan. 1962. pp.105 - 115.

Sabin, AB. Antipoliomyelitic substance in milk from human beings and certain cows. Journal of Diseases of Children 80:866-870 (1950).

Tzipori, S, Roberton, D, Chapman, C. Remission of diarrhoea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum. British Medical Journal (Clinical Research Edition) 293(6557):1276-1277 (1986).

Tzipori S, Roberton D, Chapman C. Br Med J (Clin Res Ed). 1986 Nov 15;293(6557):1276-7. Related Articles, Links, Remission of diarrhoea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum.

Theodore, Christine, et al "Immunologic Aspects of Colostrum and Milk: Development of Antibody Response to Respiratory Syncytial Virus and Bovine Serum Albumin in the Human and Rabbit Mammary Gland" Recent Advances in Mucosal Immunity (1982) (Raven Press), New York.

Tzipori S, Roberton D, Chapman C. Br Med J (Clin Res Ed). 1986 Nov 15;293(6557):1276-7. Related Articles, Links, Remission of diarrhoea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum.

Theodore, Christine, et al "Immunologic Aspects of Colostrum and Milk: Development of Antibody Response to Respiratory Syncytial Virus and Bovine Serum Albumin in the Human and Rabbit Mammary Gland" Recent Advances in Mucosal Immunity (1982) (Raven Press), New York.

Ushijima H, Dairaku M, Honnma H, Mukoyama A, Kitamura T. Kansenshogaku Zasshi. 1990 Mar;64(3):274-9. Related Articles, Links,[Immunoglobulin components and anti-viral activities in bovine colostrum][Article in Japanese],Department of Enteroviruses, National Institute of Health, Japan.
Ushijima H, Dairaku M, Honnma H, Mukoyama A, Kitamura T. (1990) Immunoglobulin components and anti-viral activities in bovine colostrum. Kansenshogaku Zasshi. 1990 Mar;64:274-279.

van Hooijdonk AC, Kussendrager KD, Steijns JM., In vivo antimicrobial and antiviral activity of components in bovine milk and colostrum involved in non-specific defence., Br J Nutr. 2000 Nov;84 Suppl 1:S127-34. Related Articles, Links,DMV International, R&D Center, PO Box 13, 5460 BA Veghel, The Netherlands.

Ylitalo S, Uhari M, Rasi S, Pudas J, Leppaluoto J. (1998) Rotaviral antibodies in the treatment of acute rotaviral gastroenteritis. Acta Paediatr. 87:264-267.
Yolken RH, Losonsky GA, Vonderfecht S, Leister F, Wee SB. (1985) Antibody to human rotavirus in cow's milk. New England Journal of Medicine. 312:605-610.

Yolken, RH, et al. Antibody to human rotavirus in cow's milk. New England Journal of Medicine 312(10):605-610 (1985). Raw and pasteurized milk contain antibodies against rotavirus, an important cause of gastroenteritis and diarrhea in infants. However, infant formulas and other sterile milk preparations had little or no anti-rotaviral activity.

Zissis G, Lambert JP, Marbehant P, Marissens D, Lobmann M, Charlier P, Delem A, Zygraich N. J Infect Dis. 1983 Dec;148(6):1061-8. Related Articles, Links, Protection studies in colostrum-deprived piglets of a bovine rotavirus vaccine candidate using human rotavirus strains for challenge.

“Colostrum has a virus antibody that acts against viral invaders. A wide range of antiviral factors were acknowledged to be present in colostrum.” from a study at the Center for Disease Control in Atlanta, Georgia, published by Dr. E. L. Palmer, et al, in the Journal of Medical Virology.

"Colostrum contains Retinoic Acid, which helps fight herpes virus. It also contains glycoprotein (kappa casein) that protects against the bacteria that cause stomach ulcers." - Dr. Raloff in Science News.

"Colostrum contains non-specific inhibitors that inhibit a wide range of respiratory illness, notably influenza viruses. Colostrum is specifically cited for its unique effectiveness against potentially deadly outbreaks of Asian flu viruses that emerge from animal/human mutations." This was published by Dr. Shortridge, et al, in the Journal of Tropical Pediatrics.

"Immunoglobulin from bovine colostrum effectively reduces and prevents viral and bacterial infections in immune deficient subjects: bone marrow recipients, premature babies, AIDS, etc." according to the New England Journal of Medicine.

Tyrell, David, "Breast Feeding and Virus Infection The Immunity of Infant Feeding" (1980) Plenum Press, N.Y., 55-61.

"Only retinoic acids, found in colostrum, conferred protection and reduced colonization of the herpes virus. Although not a cure, retinoic acids effectively reduce the herpes virus to levels (1/100th to 1/10,000th) where the body's immune system could fight off an outbreak." Dr. Charles Isaacs, et al, wrote this in Science.

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