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El Ghalbzouri, A, et al. Fibroblasts facilitate re-epithelialization in wounded human skin equivalents. Laboratory Investigation 84(1):102-112 (2004). Re-epithelialization of wounds begins with the migration of keratinocytes (skin cells) from the edges of the wound. This migration is dependent on the interaction of the keratinocytes with dermal fibroblasts and extracellular matrix. This migration is accelerated by EGF and keratinocyte growth factor.

Moller, S, et al. Insulin-like growth factor 1 (IGF-1) in burn patients. Burns 17(4):279-281 (1991). Impaired wound healing in large burns is related to suppressed levels of IGF-1 in the burn area.

Sporn MB, et al. (1983) Polypetide transforming growth factors isolated from bovine sources and used for wound healing in vivo. Science. 219:1329-1331

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